He underwent a surgical procedure to remove the appendicitis today and doctors have now advised him at least six weeks rest before he can return to cricket activities," a source in the Pakistan Cricket Board (PCB) said.
"This basically means he is definitely ruled out of the three Tests against England being held in December while he will also not be able to appear in the two Tests against New Zealand that follow," the source said.
According to the source, the PCB and the team management is unlikely to risk playing Afridi in international cricket until next April.
"Even his participation in the Pakistan Super League will depend on his recovery progress but it will also be the decision of his franchise when and how they play him in the league," the source said.