Not really. Moeen and Lyon had pretty much identical figures in the first innings, with Lyon being more economical and Moeen getting his wickets at a better SR.
In the second innings, all the Australian bowlers bowled really well, except for maybe Cummins. Hazlewood getting two yesterday, Lyon getting the three left-handers at regular intervals and then Starc blasting away the tail, without allowing them to get a few extra runs were all crucial contributions.
It is extremely simplistic to put this result down to the performances of two men. I can just as easily say that switch Smith and Root and the result would be much closer, or switch one of the Aussie pacers with their English counterparts.
Australia just out performed England ever since Smith and Marsh got together for their partnership.
Moeen had better actually 2/74 vs 2/78 - that's for statguru; I have seen both bowling for most part to know the difference beyond stats, which is exposed in 2nd innings.
On Day 4/5 such track, you don't know what surprise was waiting if Poms had to chase 170 against Lyon.